diff --git a/conda/environments/all-linux.yml b/conda/environments/all-linux.yml
new file mode 100644
index 0000000..eb997f8
--- /dev/null
+++ b/conda/environments/all-linux.yml
@@ -0,0 +1,51 @@
+name: all
+channels:
+- conda-forge
+dependencies:
+- python=3.12*
+- pip
+- uv
+- numpy
+- scipy
+- matplotlib
+- napari
+- skan
+- scikit-image
+- scikit-learn
+- ipython
+- pyqt6
+- qt6-wayland
+- statsmodels
+- pint
+- python-graphviz
+- dask
+- xarray
+- distributed
+- altair
+- bokeh
+- datashader
+- toolz
+- cytoolz
+- pandas
+- seaborn
+- jupyter
+- notebook
+- openpyxl
+- pytest
+- pytest-qt
+- pytest-cov
+- coverage
+- imageio
+- tqdm
+- cython
+- numba
+- line_profiler
+- memory_profiler
+- networkx
+- beautifulsoup4
+- plotly
+- zarr
+- ome-zarr
+- skan
+- pip:
+  - tensorstore
diff --git a/conda/environments/all-macos.yml b/conda/environments/all-macos.yml
new file mode 100644
index 0000000..356124e
--- /dev/null
+++ b/conda/environments/all-macos.yml
@@ -0,0 +1,50 @@
+name: all
+channels:
+- conda-forge
+dependencies:
+- python=3.12*
+- pip
+- uv
+- numpy
+- scipy
+- matplotlib
+- napari
+- skan
+- scikit-image
+- scikit-learn
+- ipython
+- pyqt6
+- statsmodels
+- pint
+- python-graphviz
+- dask
+- xarray
+- distributed
+- altair
+- bokeh
+- datashader
+- toolz
+- cytoolz
+- pandas
+- seaborn
+- jupyter
+- notebook
+- openpyxl
+- pytest
+- pytest-qt
+- pytest-cov
+- coverage
+- imageio
+- tqdm
+- cython
+- numba
+- line_profiler
+- memory_profiler
+- networkx
+- beautifulsoup4
+- plotly
+- zarr
+- ome-zarr
+- skan
+- pip:
+  - tensorstore
diff --git a/conda/environments/all.yml b/conda/environments/all.yml
new file mode 100644
index 0000000..356124e
--- /dev/null
+++ b/conda/environments/all.yml
@@ -0,0 +1,50 @@
+name: all
+channels:
+- conda-forge
+dependencies:
+- python=3.12*
+- pip
+- uv
+- numpy
+- scipy
+- matplotlib
+- napari
+- skan
+- scikit-image
+- scikit-learn
+- ipython
+- pyqt6
+- statsmodels
+- pint
+- python-graphviz
+- dask
+- xarray
+- distributed
+- altair
+- bokeh
+- datashader
+- toolz
+- cytoolz
+- pandas
+- seaborn
+- jupyter
+- notebook
+- openpyxl
+- pytest
+- pytest-qt
+- pytest-cov
+- coverage
+- imageio
+- tqdm
+- cython
+- numba
+- line_profiler
+- memory_profiler
+- networkx
+- beautifulsoup4
+- plotly
+- zarr
+- ome-zarr
+- skan
+- pip:
+  - tensorstore
diff --git a/fish/functions/nuke.fish b/fish/functions/nuke.fish
new file mode 100644
index 0000000..c2240f4
--- /dev/null
+++ b/fish/functions/nuke.fish
@@ -0,0 +1,21 @@
+function nuke
+    mu deactivate
+    mu env remove --name all -y
+
+    switch (uname)
+        case Linux
+            set yml_file ~/projects/dotfiles/conda/environments/all-linux.yml
+        case Darwin
+            set yml_file ~/projects/dotfiles/conda/environments/all-macos.yml
+        case '*'
+            set yml_file ~/projects/dotfiles/conda/environments/all.yml
+    end
+
+    mu env create -y -f $yml_file
+    mu activate all
+    uv pip uninstall -y napari
+    uv pip install -U -e "$HOME/projects/napari[dev,testing]"
+    uv pip install -U -e "$HOME/projects/skan"
+    uv pip install -U -e "$HOME/projects/affinder"
+    uv pip install -U -e "$HOME/projects/zarpaint"
+end